A 3D-printing graphene holding structure is disclosed in the present invention. The structure includes a pick-up element, at least one piezoelectric sensing element and a control element. The pick-up element has at least one movable area. The movable area is directly formed by 3D-printing from the 3D-printing material containing graphene, and the control element is coupled to the piezoelectric sensing element through at least two wires. The wires are formed on the outer surface, inside the piezoelectric sensing element or both. Notably, there is no electrode disposed between the wire and the piezoelectric sensing element. Therefore, the 3D-printing graphene holding structure disclosed in the present invention can directly be formed via exerting the piezoelectric material containing graphene as the piezoelectric sensing element via 3D-printing process. Furthermore, it is preferable to use graphene for its better electric conductive property so that no additional electrode would be required for serving as the electrical connection between the piezoelectric sensing element and its respective wire. Meanwhile, a 3D-printing graphene holding apparatus is also disclosed in the present invention.